My Account
My Garage
Shopping Cart

Shopping Cart

0 items in your Cart
View Cart
Subtotal
Track
My Order
MY GARAGE Select Vehicle
MY GARAGE
Categories
  • Tire and Wheel
  • RV & Marine
  • Suspension
  • Tools and Equipment
  • Body
  • Transmission
  • Brake
  • Accessories and Fluids
  • Engine
  • Electrical, Charging and Starting
  • Driveline and Axles
  • Belts and Cooling
  • Home Improvement
  • Air and Fuel Delivery
  • HVAC
  • Electrical, Lighting and Body
  • Exhaust
  • Steering
  • Powersports & Motorcycle
  • Ignition
  • Emission Control
  • Entertainment and Telematics
  • Wiper and Washer
  • Hardware and Service Supplies
  • Transfer Case
  • Multifunction Terms
  • Lawn & Garden
Manufacturers
View all
Want to receive promotions and offers?

GMC Sierra 2500 HD Engine Gaskets and Seals

Engine gaskets and seals for the GMC Sierra 2500 HD span the 2001–2024 model years, covering everything from cylinder head gaskets to intake manifold and valve cover sets. Pick your GMC Sierra 2500 HD's year above to narrow the list to engine gaskets and seals with confirmed fitment. Every part shown is checked against our vehicle data.

151 - 179 of 179 results

Best Seller Free Shipping
Picture of Cometic C5477-098 GM MLS Cylinder Head Gasket Bore - LS1/LS2/LS3/LS6 4.000

Cometic C5477-098 GM MLS Cylinder Head Gasket Bore - LS1/LS2/LS3/LS6 4.000

75 reviews
Part: C5477-098
Vehicle Specific
$140.43
Ships from manufacturer
Picture for manufacturer Cometic
Best Seller Free Shipping
Picture of Cometic C5317-032 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.130

Cometic C5317-032 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.130

47 reviews
Part: C5317-032
Vehicle Specific
$98.30
Ships from manufacturer
Picture for manufacturer Cometic
Best Seller Free Shipping
Picture of Cometic C5489-053 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.100

Cometic C5489-053 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.100

71 reviews
Part: C5489-053
Vehicle Specific
$123.70
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of Cometic C5489-089 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.100

Cometic C5489-089 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.100

78 reviews
Part: C5489-089
Vehicle Specific
$140.10
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of Cometic C5477-049 MLS Cylinder Head Gasket GM Bore - LS1/LS2/LS3/LS6 4.000

Cometic C5477-049 MLS Cylinder Head Gasket GM Bore - LS1/LS2/LS3/LS6 4.000

70 reviews
Part: C5477-049
Vehicle Specific
$98.14
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of Cometic C5765-080 MLS Cylinder Head Gasket GM Vortec Gen VII Big Block - 8100 L18 V8

Cometic C5765-080 MLS Cylinder Head Gasket GM Vortec Gen VII Big Block - 8100 L18 V8

35 reviews
Part: C5765-080
Vehicle Specific
$158.24
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of Cometic C5318-089 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.160

Cometic C5318-089 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.160

34 reviews
Part: C5318-089
Vehicle Specific
$140.10
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of Cometic C5319-080 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.190

Cometic C5319-080 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.190

65 reviews
Part: C5319-080
Vehicle Specific
$126.82
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of Cometic C5317-092 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.130

Cometic C5317-092 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.130

36 reviews
Part: C5317-092
Vehicle Specific
$140.10
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of Cometic C15517-040 MLS Cylinder Head Gasket GM Bore - LS1/LS2/LS3/LS6 4.200

Cometic C15517-040 MLS Cylinder Head Gasket GM Bore - LS1/LS2/LS3/LS6 4.200

62 reviews
Part: C15517-040
Vehicle Specific
$97.39
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of Cometic C5319-056 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.190

Cometic C5319-056 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.190

60 reviews
Part: C5319-056
Vehicle Specific
$101.32
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of Cometic C5014-032 GM MLS Cylinder Head Gasket Bore - LS1/LS2/LS3/LS6 4.150 032

Cometic C5014-032 GM MLS Cylinder Head Gasket Bore - LS1/LS2/LS3/LS6 4.150 032

47 reviews
Part: C5014-032
Vehicle Specific
$117.72
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of Cometic C5751-086 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.060

Cometic C5751-086 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.060

55 reviews
Part: C5751-086
Vehicle Specific
$139.28
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of Cometic C5489-140 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.100

Cometic C5489-140 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.100

56 reviews
Part: C5489-140
Vehicle Specific
$231.78
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of Cometic C5319-066 MLS Cylinder Head Gasket GM Bore - LS1/LS2/LS3/LS6 4.190

Cometic C5319-066 MLS Cylinder Head Gasket GM Bore - LS1/LS2/LS3/LS6 4.190

63 reviews
Part: C5319-066
Vehicle Specific
$101.32
Ships from manufacturer
Picture for manufacturer Cometic
Picture of Cometic C15030 GM Gen III/IV LS Engine Valve Cover Grommet Set Representative Photo, actual item may vary

Cometic C15030 GM Gen III/IV LS Engine Valve Cover Grommet Set

40 reviews
Part: C15030
Vehicle Specific
$11.52
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of Cometic C15375-053 GM Duramax MLX Cylinder Head Gasket Bore - 4.130 053

Cometic C15375-053 GM Duramax MLX Cylinder Head Gasket Bore - 4.130 053

62 reviews
Part: C15375-053
Vehicle Specific
$192.82
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of Cometic C15376-053 GM Duramax MLX Cylinder Head Gasket Bore - 053 4.130

Cometic C15376-053 GM Duramax MLX Cylinder Head Gasket Bore - 053 4.130

53 reviews
Part: C15376-053
Vehicle Specific
$192.82
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of Cometic PRO3012B Gm Lml/lmm/lgh Duramax Bottom End Gasket Kit

Cometic PRO3012B Gm Lml/lmm/lgh Duramax Bottom End Gasket Kit

69 reviews
Part: PRO3012B
Vehicle Specific
$204.84
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of MAHLE HS4920A Victor Reinz Cylinder Head Gasket - Set

MAHLE HS4920A Victor Reinz Cylinder Head Gasket - Set

8 reviews
Part: HS4920A
Vehicle Specific
$119.44
2 left at this price
Picture for manufacturer MAHLE
Picture of MAHLE JV1691 Rear Main Engine Crankshaft Seal Gasket Set

MAHLE JV1691 Rear Main Engine Crankshaft Seal Gasket Set

6 reviews
Part: JV1691
Vehicle Specific
$35.20
2 left at this price
Picture for manufacturer MAHLE
Free Shipping
Picture of MAHLE HS5713X Victor Reinz Cylinder Head Gasket - Set

MAHLE HS5713X Victor Reinz Cylinder Head Gasket - Set

67 reviews
Part: HS5713X
Vehicle Specific
$81.97
4 left at this price
Picture for manufacturer MAHLE
Free Shipping
Picture of MAHLE HS54580B Victor Reinz Cylinder Head Gasket - Set

MAHLE HS54580B Victor Reinz Cylinder Head Gasket - Set

71 reviews
Part: HS54580B
Vehicle Specific
$248.26
2 left at this price
Picture for manufacturer MAHLE
Free Shipping
Picture of MAHLE HS54348 Victor Reinz Cylinder Head Gasket - Set

MAHLE HS54348 Victor Reinz Cylinder Head Gasket - Set

45 reviews
Part: HS54348
Vehicle Specific
$378.72
3 left at this price
Picture for manufacturer MAHLE
Free Shipping
Picture of MAHLE HS54119 Victor Reinz Cylinder Head Gasket - Set

MAHLE HS54119 Victor Reinz Cylinder Head Gasket - Set

29 reviews
Part: HS54119
Vehicle Specific
$133.30
1 left at this price
Picture for manufacturer MAHLE
Free Shipping
Picture of MAHLE HS54578E Victor Reinz Cylinder Head Gasket - Set

MAHLE HS54578E Victor Reinz Cylinder Head Gasket - Set

33 reviews
Part: HS54578E
Vehicle Specific
$192.88
1 left at this price
Picture for manufacturer MAHLE
Free Shipping
Picture of MAHLE HS54442D Engine Cylinder Head Gasket - Set

MAHLE HS54442D Engine Cylinder Head Gasket - Set

31 reviews
Part: HS54442D
Vehicle Specific
$334.64
In Stock (10+)
Picture for manufacturer MAHLE
Free Shipping
Picture of MAHLE 95-3727 Full Engine Gasket Set Without Head Gasket 6.6L Duramax Diesel

MAHLE 95-3727 Full Engine Gasket Set Without Head Gasket 6.6L Duramax Diesel

58 reviews
Part: 95-3727
Vehicle Specific
$371.28
2 left at this price
Picture for manufacturer MAHLE
Free Shipping
Picture of MAHLE 55524 Engine Cylinder Head Gasket

MAHLE 55524 Engine Cylinder Head Gasket

65 reviews
Part: 55524
$96.77
In Stock (10+)
Picture for manufacturer MAHLE

What's here for your GMC Sierra 2500 HD

  • Engine cylinder head gaskets
  • Engine intake manifold gasket sets
  • Engine valve cover gasket sets
  • Engine valve cover gaskets
  • Performance and heavy-duty gasket kits
  • OE replacement and rubber seal options

The widest selection here comes from Cometic, MAHLE, Victor, and Fel-Pro, offering a range that spans OE-replacement styles, heavy-duty configurations, and performance-oriented kits in various materials and positions — front, rear, and full-set options alike. Other categories GMC Sierra 2500 HD owners shop for: GMC Sierra 2500 HD Shocks and Struts, GMC Sierra 2500 HD Exterior Lights and GMC Sierra 2500 HD Springs and Suspension Parts, or browse all GMC Sierra 2500 HD parts and accessories.