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GMC Sierra 2500 HD Engine Gaskets and Seals

Engine gaskets and seals for the GMC Sierra 2500 HD span the 2001–2024 model years, covering everything from cylinder head gaskets to intake manifold and valve cover sets. Pick your GMC Sierra 2500 HD's year above to narrow the list to engine gaskets and seals with confirmed fitment. Every part shown is checked against our vehicle data.

121 - 150 of 179 results

Best Seller Free Shipping
Picture of Cometic C5477-066 GM MLS Cylinder Head Gasket Bore - LS1/LS2/LS3/LS6 4.000

Cometic C5477-066 GM MLS Cylinder Head Gasket Bore - LS1/LS2/LS3/LS6 4.000

51 reviews
Part: C5477-066
Vehicle Specific
$129.83
Ships from manufacturer
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Picture of Cometic C5319-066 MLS Cylinder Head Gasket GM Bore - LS1/LS2/LS3/LS6 4.190

Cometic C5319-066 MLS Cylinder Head Gasket GM Bore - LS1/LS2/LS3/LS6 4.190

63 reviews
Part: C5319-066
Vehicle Specific
$101.32
Ships from manufacturer
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Picture of Cometic C5319-027 MLS Cylinder Head Gasket GM Bore - LS1/LS2/LS3/LS6 4.190

Cometic C5319-027 MLS Cylinder Head Gasket GM Bore - LS1/LS2/LS3/LS6 4.190

38 reviews
Part: C5319-027
Vehicle Specific
$97.39
Ships from manufacturer
Picture for manufacturer Cometic
Picture of Cometic C15030 GM Gen III/IV LS Engine Valve Cover Grommet Set

Cometic C15030 GM Gen III/IV LS Engine Valve Cover Grommet Set

40 reviews
Part: C15030
Vehicle Specific
$11.52
Ships from manufacturer
Picture for manufacturer Cometic
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Picture of Cometic C15524-060 MLS Cylinder Head Gasket GM Bore - LS1/LS2/LS3/LS6 4.200

Cometic C15524-060 MLS Cylinder Head Gasket GM Bore - LS1/LS2/LS3/LS6 4.200

74 reviews
Part: C15524-060
Vehicle Specific
$129.83
Ships from manufacturer
Picture for manufacturer Cometic
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Picture of Cometic C5319-075 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.190

Cometic C5319-075 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.190

10 reviews
Part: C5319-075
Vehicle Specific
$101.32
Ships from manufacturer
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Picture of Cometic C15514-051 MLS Cylinder Head Gasket GM Bore - LS1/LS2/LS3/LS6 4.070

Cometic C15514-051 MLS Cylinder Head Gasket GM Bore - LS1/LS2/LS3/LS6 4.070

19 reviews
Part: C15514-051
Vehicle Specific
$97.41
Ships from manufacturer
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Picture of Cometic C15375-062 Duramax Cylinder Head Gasket .062" MLX 4.130" Bore

Cometic C15375-062 Duramax Cylinder Head Gasket .062" MLX 4.130" Bore

61 reviews
Part: C15375-062
Vehicle Specific
$195.01
Ships from manufacturer
Picture for manufacturer Cometic
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Picture of Cometic C15515-040 MLS Cylinder Head Gasket GM Gen III/IV Bore - for LS1/LS2/LS3/LS6 4.030

Cometic C15515-040 MLS Cylinder Head Gasket GM Gen III/IV Bore - for LS1/LS2/LS3/LS6 4.030

9 reviews
Part: C15515-040
Vehicle Specific
$100.42
Ships from manufacturer
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Picture of Cometic C15496-051 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.080

Cometic C15496-051 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.080

75 reviews
Part: C15496-051
Vehicle Specific
$97.41
Ships from manufacturer
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Picture of Cometic C5319-092 MLS Cylinder Head Gasket GM Gen III/IV Bore - for LS1/LS2/LS3/LS6 4.190

Cometic C5319-092 MLS Cylinder Head Gasket GM Gen III/IV Bore - for LS1/LS2/LS3/LS6 4.190

18 reviews
Part: C5319-092
Vehicle Specific
$126.82
Ships from manufacturer
Picture for manufacturer Cometic
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Picture of Cometic C5319-070 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.190

Cometic C5319-070 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.190

19 reviews
Part: C5319-070
Vehicle Specific
$101.32
Ships from manufacturer
Picture for manufacturer Cometic
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Picture of Cometic C5317-034 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.130

Cometic C5317-034 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.130

8 reviews
Part: C5317-034
Vehicle Specific
$98.30
Ships from manufacturer
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Picture of Cometic C15482-062 GM Gen-3/4 LS V8 Cylinder Head Gasket .062" MLX 3.940" Bore

Cometic C15482-062 GM Gen-3/4 LS V8 Cylinder Head Gasket .062" MLX 3.940" Bore

42 reviews
Part: C15482-062
Vehicle Specific
$124.72
Ships from manufacturer
Picture for manufacturer Cometic
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Picture of Cometic C15508-051 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.085

Cometic C15508-051 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.085

6 reviews
Part: C15508-051
Vehicle Specific
$100.42
Ships from manufacturer
Picture for manufacturer Cometic
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Picture of Cometic C15494-051 GM MLS Cylinder Head Gasket Bore - LS1/LS2/LS3/LS6 4.030

Cometic C15494-051 GM MLS Cylinder Head Gasket Bore - LS1/LS2/LS3/LS6 4.030

59 reviews
Part: C15494-051
Vehicle Specific
$99.60
Ships from manufacturer
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Picture of Cometic C5319-098 GM MLS Cylinder Head Gasket Bore Thick - LS1/LS2/LS3/LS6 4.190 098

Cometic C5319-098 GM MLS Cylinder Head Gasket Bore Thick - LS1/LS2/LS3/LS6 4.190 098

61 reviews
Part: C5319-098
Vehicle Specific
$126.82
Ships from manufacturer
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Picture of Cometic C15517-040 MLS Cylinder Head Gasket GM Bore - LS1/LS2/LS3/LS6 4.200

Cometic C15517-040 MLS Cylinder Head Gasket GM Bore - LS1/LS2/LS3/LS6 4.200

62 reviews
Part: C15517-040
Vehicle Specific
$97.39
Ships from manufacturer
Picture for manufacturer Cometic
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Picture of Cometic C5764-089 MLS Cylinder Head Gasket GM Vortec Gen VII Big Block - 8100 L18 V8

Cometic C5764-089 MLS Cylinder Head Gasket GM Vortec Gen VII Big Block - 8100 L18 V8

73 reviews
Part: C5764-089
Vehicle Specific
$157.91
Ships from manufacturer
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Picture of Cometic C5764-056 MLS Cylinder Head Gasket GM Vortec Gen VII Big Block - 8100 L18 V8

Cometic C5764-056 MLS Cylinder Head Gasket GM Vortec Gen VII Big Block - 8100 L18 V8

16 reviews
Part: C5764-056
Vehicle Specific
$147.82
Ships from manufacturer
Picture for manufacturer Cometic
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Picture of Cometic C5489-075 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.100

Cometic C5489-075 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.100

5 reviews
Part: C5489-075
Vehicle Specific
$126.82
Ships from manufacturer
Picture for manufacturer Cometic
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Picture of Cometic C5489-027 MLS Cylinder Head Gasket GM Bore - LS1/LS2/LS3/LS6 4.100

Cometic C5489-027 MLS Cylinder Head Gasket GM Bore - LS1/LS2/LS3/LS6 4.100

75 reviews
Part: C5489-027
Vehicle Specific
$98.30
Ships from manufacturer
Picture for manufacturer Cometic
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Picture of Cometic C5764-070 GM Vortec 8100 Gen-VII MLS Cylinder Head Gasket 4.280" Bore

Cometic C5764-070 GM Vortec 8100 Gen-VII MLS Cylinder Head Gasket 4.280" Bore

29 reviews
Part: C5764-070
Vehicle Specific
$147.82
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of Cometic C5318-089 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.160

Cometic C5318-089 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.160

34 reviews
Part: C5318-089
Vehicle Specific
$140.10
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of Cometic C5477-092 MLS Cylinder Head Gasket GM Gen III/IV Bore - for LS1/LS2/LS3/LS6 4.000

Cometic C5477-092 MLS Cylinder Head Gasket GM Gen III/IV Bore - for LS1/LS2/LS3/LS6 4.000

75 reviews
Part: C5477-092
Vehicle Specific
$140.43
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of Cometic C5765-080 MLS Cylinder Head Gasket GM Vortec Gen VII Big Block - 8100 L18 V8

Cometic C5765-080 MLS Cylinder Head Gasket GM Vortec Gen VII Big Block - 8100 L18 V8

35 reviews
Part: C5765-080
Vehicle Specific
$158.24
Ships from manufacturer
Picture for manufacturer Cometic
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Picture of Cometic C5751-084 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.060

Cometic C5751-084 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.060

15 reviews
Part: C5751-084
Vehicle Specific
$137.09
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of Cometic C5489-089 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.100

Cometic C5489-089 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.100

78 reviews
Part: C5489-089
Vehicle Specific
$140.10
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of Cometic C5317-032 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.130

Cometic C5317-032 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.130

47 reviews
Part: C5317-032
Vehicle Specific
$98.30
Ships from manufacturer
Picture for manufacturer Cometic
Free Shipping
Picture of Cometic C5317-054 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.130 054

Cometic C5317-054 MLS Cylinder Head Gasket GM Gen III/IV Bore - LS1/LS2/LS3/LS6 4.130 054

52 reviews
Part: C5317-054
Vehicle Specific
$129.83
Ships from manufacturer
Picture for manufacturer Cometic

What's here for your GMC Sierra 2500 HD

  • Engine cylinder head gaskets
  • Engine intake manifold gasket sets
  • Engine valve cover gasket sets
  • Engine valve cover gaskets
  • Performance and heavy-duty gasket kits
  • OE replacement and rubber seal options

The widest selection here comes from Cometic, MAHLE, Victor, and Fel-Pro, offering a range that spans OE-replacement styles, heavy-duty configurations, and performance-oriented kits in various materials and positions — front, rear, and full-set options alike. Other categories GMC Sierra 2500 HD owners shop for: GMC Sierra 2500 HD Shocks and Struts, GMC Sierra 2500 HD Exterior Lights and GMC Sierra 2500 HD Springs and Suspension Parts, or browse all GMC Sierra 2500 HD parts and accessories.