GMC Sierra 2500 HD Spark Plug Wires and Ignition Wiring
This page brings together spark plug wires and ignition wiring for the GMC Sierra 2500 HD, covering model years 2001–2022. The range includes complete wire sets, individual spark plug wires, and boot kits in OE-replacement and performance styles. Select your year above and we'll show only the spark plug wires and ignition wiring that fit your GMC Sierra 2500 HD. Fitment is checked against our vehicle data for every part listed.
Edelbrock 22716 Max-Fire Ultra-Spark 50 GM LS Truck Spark Plug Wire Set
MSD 5574 Street Fire Spark Plug Wire Set GM LS Truck 4.8L 5.3L 6.0L
FAST 255-2420 FireWire LS Series Spark Plug Wire Set GM Truck 4.8L 5.3L 6.0L 6.2L
NGK 51016 Spark Plug Wire Set RC-GMX092 Silicone Ferro Mag Core Ignition Wires
NGK 51033 Spark Plug Wire Set Ferro Mag Core Silicone 10.5in Lead
NGK 51440 Spark Plug Wire Set RC-GMX113 Blue Silicone Ignition Wires
NGK 51438 Spark Plug Wire Set RC-GMX109 Ferro Mag Core Silicone Ignition Wires
What's here for your GMC Sierra 2500 HD
- Spark Plug Wire Sets — complete sets in OE-replacement and performance configurations, including ceramic-coated options
- Spark Plug Wires — individual wires available in multiple styles including black performance designs
- Spark Plug Boot Kits — ceramic and standard boot kits for replacing worn or damaged wire ends
The widest selection here comes from TAYLOR, Standard Motor Products, MSD, and Delphi, spanning performance and OE-style fitments across the 2001–2022 model range. Other categories GMC Sierra 2500 HD owners shop for: GMC Sierra 2500 HD Shocks and Struts, GMC Sierra 2500 HD Exterior Lights and GMC Sierra 2500 HD Springs and Suspension Parts, or browse all GMC Sierra 2500 HD parts and accessories.